COVID-19 infection may lead to diabetes by up-regulating the immune system

He COVID-19 and his consequences it is still under study. With some perspective and statistical data, scientists adjust to post-infection risks. However, according to a study that has just been published in JAMA Network Open, the infection produced by this disease increases the possibility of developing diabetesconfirming previous research and highlighting the long-term health risks posed by the virus.

The study, based on health records of nearly 24,000 adults with at least one documented COVID-19 infection who received treatment at Cedars-Sinai Health System in Los Angeles, United States, between 2020 and 2022 , found higher rates of diabetes recent onset within 90 days of COVID infection, than those recorded among those who did not, and compared to previous numbers.

The Omicron variant was the most impactful in the world (Getty Images)
The Omicron variant was the most impactful in the world (Getty Images)

The odds of being diagnosed with new-onset diabetes were 58% greater after infection than before, the scientists found. The finding is consistent with a growing body of research showing that patients who contract COVID are at increased risk of being diagnosed with a variety of metabolic and cardiovascular issues in the months following infection.

This also suggests that this increased risk persisted with micron, the researchers said, the variant of the coronavirus that has dominated much of the world for more than a year. The results also suggest that the vaccination it may help protect against the risk of diabetes after infection, as the risk of diabetes appears to be lower in vaccinated patients at the time of infection.

“Further research will be needed to confirm the theory, but we are confident that vaccination is an important tool in protection against COVID-19,” said Alan Kwan, cardiovascular physician at the Smidt Heart Institute at Cedars-Sinai and lead author of the study.

After having COVID-19, the risks of suffering from cardiovascular problems also increase (Gettyimages)
After having COVID-19, the risks of suffering from cardiovascular problems also increase (Gettyimages)

There’s still a lot that specialists don’t understand about how COVID-19 affects the body. Susan Cheng, professor of cardiology and lead author of the study, said that “the team’s findings expand the understanding of disease by medicine and open up new questions. While not certain, the data suggests that COVID infection could act as a disease accelerant in some settings, increasing the risk of a diagnosis people might have received later in life. A person with a pre-existing risk of diabetes might, for example, be more likely to develop the disease at 45 or 55 years after infection than at 65,” Cheng added.

As the COVID-19 pandemic has progressed, evidence has accumulated showing that infection increases the risk of a host of conditions throughout the body, and a huge body of research shows that survivors run a increased risk of developing various neurological conditions there psychiatric, cardiovascular and metabolic problems.

Diabetes screening should be recommended for people after recovering from mild forms of COVID-19
Diabetes screening should be recommended for people after recovering from mild forms of COVID-19

The risk of developing diabetes, a serious and lifelong condition that affects how the body handles sugar, is also high. The condition is manageable, but it remains one of leading causes of death and is a major contributor to cardiovascular disease. The cost of insulin needed by diabetics is also significant.

“The mechanisms contributing to the risk of post-infectious diabetes remain unclear, although persistent inflammation contributing to insulin resistance is a proposed pathway. Further studies are needed to understand the cardiometabolic sequelae of COVID-19 and whether vaccination against the disease mitigates the risk of cardiometabolic disease in general,” Cheng concluded.

Alan C. Kwan, Joseph E. Ebinger, Patrick Botting, Jesse Navarrette and Brian Claggett also participated in this research.

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